Risperdal Case Evaluation

Risperdal contains risperidone, an atypical antipsychotic belonging to the chemical class of benzisoxazole derivatives. It is used to treat schizophrenia and acute mania, or mixed episodes of bipolar disorders and autism spectrum disorders in children and adolescents FDA approval: Risperdal was first approved by the Food and Drug Administration (FDA) to treat schizophrenia in 1993. 2003: Short-term treatment of bipolar I disorder in adults. 2006: Treatment of irritability associated with spectrum disorders in children and adolescents 5 to 16 years old. 2007: Schizophrenia in adolescents ages 13 to 17 and short-term treatment of bipolar I disorder in children and adolescents ages 10 to 17. Lawsuit Focus – Drug injury. The drug is also used “off label” for attention deficit hyperactivity disorder (ADHD), anxiety, sleep difficulties and depression.

Complications Include:

  • Development of Gynecomastia (Male breast growth),
    swollen breast tissue or nipple discharge
  • Hyperprolactinemia
  • Galactorrhea, amenorrhea, gynecomastia, and impotence
  • Other Complications
  • Movement disorder – Increased risk of movement disorders
  • such as Extrapyramidal symptoms (EPS) and tardive dyskinesia
  • Orthostatic Hypotension
  • Leukopenia, Neutropenia, and Agranulocytosis
  • Somnolence
  • Seizures
  • Dysphagia
  • Priapism
  • Neuroleptic Malignant Syndrome
  • Cerebrovascular events, including stroke, in elderly patients
    with dementia related psychosis
  • Production of prolactin
  • Pituitary tumors
  • Tardive Dyskinesia
  • Stroke
  • Neuroleptic Malignant Syndrome (NMS)
  • Increased risk of sudden death from heart attack
  • Diabetes, hyperglycemia and other blood
    sugar side effects
  • Weight gain, potentially rapid and extreme
  • Suicide, suicidal thoughts
  • Pancreatitis
  • Bone loss
  • Cellulitis
  • Neutropenia
  • Increased mortality in the elderly with dementia
    and related psychosis

Case Evaluation Criteria:

Matrix Sample Case Evaluation

Risperdal

Risperdal

1. Whether the patient was prescribed Risperdal?

2. Reason for prescription? Is the patient really in need of Risperdal? Is it an off label use?

3. Did the patient have any preexisting conditions, allergies or contraindications for the Risperdal drug?

4. Dosage and Intake details (to be included under pharmacy log) Critical Review of Physician Drug Prescription Details Pharmacy Dispensing Details Pharmacy Refill Details Details of Pharmacy Dispensing Details are taken as Confirmatory

5. Did the patient develop Gynecomastia or lactation after Risperdal intake?

6. When and where was the injury diagnosed?

7. Treatment/management – Such as liposuction, Operative procedure (Mastectomy), indications, complications.

8. Follow-up visits for Surgical treatment/management

9. Outcome/prognosis

10. Any recurrence of breast growth?

11. Any prior significant history?